By Jacqueline A. Hubbard,Devin K. Binder
Epilepsy is a devastating workforce of neurological issues characterised by way of periodic and unpredictable seizure task within the mind. there's a serious desire for brand new medicinal drugs and ways given than at the least one-third of all epilepsy sufferers aren't made freed from seizures through latest medicines and develop into "medically refractory". a lot of epilepsy study has eager about neuronal healing ambitions, yet present antiepileptic medications usually reason serious cognitive, developmental, and behavioral uncomfortable side effects. fresh findings point out a severe contribution of astrocytes, star-shaped glial cells within the mind, to neuronal and community excitability and seizure job. in addition, many very important mobile and molecular adjustments ensue in astrocytes in epileptic tissue in either people and animal types of epilepsy. The target of Astrocytes and Epilepsy is to comprehensively evaluate intriguing findings linking adjustments in astrocytes to useful alterations accountable for epilepsy for the 1st time in ebook layout. those insights into astrocyte contribution to seizure susceptibility point out that astrocytes may perhaps characterize a big new healing goal within the keep an eye on of epilepsy.
Astrocytes and Epilepsy contains heritage explanatory textual content on astrocyte morphology and body structure, epilepsy types and syndromes, and facts from either human tissue experiences and animal types linking useful alterations in astrocytes to epilepsy. fantastically labelled diagrams are provided and correct figures from the literature are reproduced to explain key findings and ideas during this quickly rising box. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators in addition to neurologists and different experts taking good care of sufferers with epilepsy.
- Presents the 1st finished publication to synthesize old and up to date study on astrocytes and epilepsy into one coherent volume
- Provides an excellent source at the box of astrocyte biology and astrocyte-neuron interactions
- Details power healing pursuits, together with chapters on hole junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation
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