Cell Biology

Neuronal Network Dynamics in 2D and 3D in vitro by Monica Frega

By Monica Frega

The book
presents a brand new, robust version of neuronal networks, such as a
three-dimensional neuronal tradition within which 3D neuronal networks are coupled to
micro-electrode-arrays (MEAs). It discusses the most benefits of the
three-dimensional approach in comparison to its two-dimensional counterpart, and shows
that the community dynamics, recorded in the course of either spontaneous and stimulated
activity, differs among the 2 versions, with the 3D procedure being greater able
to emulate the in vivo behaviour of neural networks. The booklet deals an
extensive research of the process, from the theoretical heritage, to its
design and functions in neuro-pharmacological stories. in addition, it
includes a concise but entire creation to either 2nd and 3D neuronal
networks coupled to MEAs, and discusses the benefits, barriers and
challenges in their functions as mobile and tissue-like in vitro experimental version systems.

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